Disease and Treatment Burden

This field of study includes clinical trials that address approaches to prevent and/or treat symptoms, distress, and functional burden caused by cancer and/or cancer treatment.

This is an important emerging field of science that may improve quality of life for cancer patients and, at times, may also improve the length of life for such patients.

Topics of special interest are:

  • Clinical trials that are supported by rigorous and compelling preliminary pre-clinical and clinical research
  • Clinical trials investigating all types of treatments for symptoms, such as behavioral, integrative, pharmaceutical, and other non-pharmacological interventions
  • Clinical trials that test supportive care interventions that would be well-suited for broad dissemination in the community oncology environment
  • Correlative intervention studies to understand the biological mechanism or to understand patients at the highest risk so that therapies can be personalized, thus mitigating the symptoms caused by the main treatment being investigated

Funding Opportunities

Chronic Pain Research

This request for proposal (RFP) was designed based on patient needs. It will focus on interventions for the prevention and/or treatment of cancer-related chronic pain. Specifically, the RFP welcome proposals focused on all types of cancer-related chronic pain, including but not limited to post-surgical pain, lymphedema-related pain, chemotherapy-induced peripheral neuropathy, phantom pain, aromatase inhibitor-related joint pain, referred pain and bone metastasis pain.

Open Call

We accept Letters of Intent (LOIs) all year round with cutoff deadlines for internal assessment three times per year. Once you have submitted your LOI, you will receive further information regarding timing and next steps.

Pre-application Grants

Pre-application grants provide gap funding to support patient experts’ helping to develop grant applications/ protocols.

Focus Area Grants

University Health Network


The University of Texas M.D. Anderson Cancer Center

Optimizing Neurofeedback to Treat CIPN

University of Bern

Surgical versus conservative therapy for breast cancer related lymphoedema

Disease and Treatment Burden Materials

Integrative Medicine for Pain Management in Oncology - Journal of Clinical Oncology - 2022

Focus Areas

Science of Early Detection and Intervention

Advancing Cancer Research in Underserved Areas

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