Cancer research
– our focus areas

To focus our efforts and increase our impact, we have designed two umbrella focus areas under the themes Improved Patient Outcomes and Science of Prevention and Detection.

Funding Approach


Short timeframes, maximum impact

To highlight our sense of urgency, we expect that clinical research projects should result in patient impact within 5 years and are expected to start within 6 months of approval unless otherwise agreed.


Partnerships to maximize reach

We are one of several players in this area, and we share objectives with a broad range organizations worldwide. We partner with them in order to leverage resources to accelerate the improvement of patient treatment options and quality of life everywhere.

Focus Areas

To keep our efforts focused and increase our impact, we have developed two umbrella themes: Improved Patient Outcomes and Science of Prevention and Detection.

Improved patient Outcomes

Therapy optimization
We aim to support research that advances therapeutic approaches that provide the best possible outcome with the least toxicity for each individual patient.
Disease and treatment burden
This field of study includes clinical trials that address approaches to prevent and/or treat symptoms, distress, and functional burden caused by cancer and/or cancer treatment.
Implementation research
There is much work to be done in the area of implementation research for cancer care.

Science of prevention and detection

Improve detection of genetic and modular changes for monitoring of people at increased risk of cancer
Selected primary prevention strategy trials
Genetic, molecular and imaging technologies to noninvasively identify or monitor the presence or precursors of cancer
Better characterize aggressive cancers through the use of biomarkers or other technologies to personalize detection/monitoring

How to apply for a clinical cancer research grant

Whether you are an academic institution interested in applying for a grant or another not-for-profit organization keen to tackle critical cancer related issues together, we want to hear from you.

We receive LOI’s all year round and do not have specific deadlines. Once you have submitted your LOI you will receive further information regarding the timing and next steps. Our board meetings take place in May, August, and December. The evaluation period is between 3 and 6 months.

If your project meets our funding criteria, we will contact you and extend an invitation for you to submit a full grant application for further consideration. If you are uncertain about the eligibility of your proposal, please email us at before beginning an application.

A selection of current projects and their descriptions, explaining how they fit in our funding program, are available here.

Before you apply, check to see if you qualify for a pre-application grant to support patient involvement

Pre-application Form & Guidelines

Get started with the letter of intent Guidelines

All LOIs must be submitted in accordance with the submission guidelines via proposalCENTRAL 

Step 1

Establish a user account to submit a grant application. If you have an existing user account with proposalCENTRAL, simply log in to the platform with your details. 

Step 2

To begin a LOI, select "Grant Opportunities". Find "Rising Tide Foundation for Clinical Cancer Research". Alternatively, you can find our grant offerings at the following links:

Rising Tide Foundation for Clinical Cancer Research

​Also, we now have links that will specifically go to the Clinical Cancer Research program here 

​Step 3

Choose your program and click the "Apply Now" link to download the LOI template from proposalCENTRAL.

Step 4

Complete all fields in the application form and in the provided template(s). Please note that the LOI application for RTFCCR is limited to 5 pages, and cited publications and supporting documents are not included in this page number limit. For Freedom in Practice, follow the guidance on characters in the LOI template. All requested documents must be uploaded in PDF format. They must be in 10 point and Open Sans font.

For more information or in case of technical issues, kindly refer to the FAQ section on proposalCENTRAL or contact the team at

For any project-related queries, applicants should refer to our Programmatic Guidelines, which can be downloaded from proposalCENTRAL.

Application review

Only applicants with LOIs deemed most meritorious and aligned with our grant programs’ focus will be invited to submit full applications. Instructions for the submission of full applications are provided after the LOI evaluation. 

Clinical Cancer Research Stories – Why it matters

Our objective is to accelerate progress to improve the lives of people living with cancer today and bring forward the day when a cure for cancer is finally realized. Find some inspiring stories right here.

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