Grantee Name: Dr. Miriam Cremer
Organization: Cleveland Clinic Foundation
Project Name: Development of Alternative Ablation Device for Cervical Pre-Cancer Treatment
Funding Year: 2017
Project period: 4 years
Development of Alternative Ablation Device for Cervical Pre-Cancer Treatment
The trial aims to demonstrate that the cure rates of the CryoPen® and the thermoablator are non-inferior to the cure rate of CO2-based cryotherapy; determine patient acceptability of each therapy type by actively assessing side effects and monitoring pain levels related to treatment; evaluate screening methods one-year post-ablation by comparing the sensitivity of low-cost HPV screening tests, HPV DNA genotyping tests, cytology, and biopsies.