Grantee Name: Prof. Bindra Ranjit
Organization: Yale University
Country: USA
Project Name:
Phase 2 Study of the PARP Inhibitor Olaparib in IDH1/2-mutant solid tumors
Funding Year:
2018
Project period: 3 years
Phase 2 Study of the PARP Inhibitor Olaparib in IDH1/2-mutant solid tumors
To conduct a comprehensive series of correlative studies in tumor biopsies to identify which patients with IDH1/2 tumor mutations respond best to the DNA repair inhibitor, Olaparib.