Implementation Research

There is a significant gap between clinical trials’ positive outcomes and their implementation in everyday practice, which poses a significant challenge in providing optimal care to cancer patients.

Implementation science, an emerging research field, employs a scientific approach to identify the best methods for incorporating proven, effective interventions into routine clinical practice. Additionally, successfully implementing evidence-based care options in various settings, including underserved areas, will reduce cancer disparities.

Hybrid designs

Among many design types of implementation research, RTFCCR specifically welcomes the hybrid effectiveness-implementation design, blending the components of clinical effectiveness and implementation research. 

Hybrid Type 1

Testing a clinical intervention while gathering information on its delivery during the effectiveness trial and/or on its potential for implementation in a real-world situation.

Hybrid Type 2

Simultaneous testing of a clinical intervention and an implementation intervention/strategy.

Hybrid Type 3

Testing an implementation intervention/strategy while observing/gathering information on the clinical intervention and related outcomes.

For more information, please read: Curran GM, Bauer M, Mittman B, Pyne JM, Stetler C. Effectiveness-implementation hybrid designs: combining elements of clinical effectiveness and implementation research to enhance public health impact. Med Care. 2012 Mar;50(3):217-26. doi: 10.1097/MLR.0b013e3182408812. PMID: 22310560; PMCID: PMC3731143.

Funding Opportunities

Open Call

We accept Letters of Intent (LOIs) all year round with cutoff deadlines for internal assessment three times per year. Once you have submitted your LOI, you will receive further information regarding timing and next steps.

Pre-application Grants

Pre-application grants provide gap funding to support patient experts’ helping to develop grant applications/ protocols.

Request for Proposal

At the moment there are no other open funding opportunities.

Focus Area Grants

University of Texas M.D. Anderson Cancer Center

A technology-enabled approach to enhancing outpatient symptom management in vulnerable cancer patients

Implementation Research Materials

Effectiveness-implementation Hybrid Designs-MedCare2012

Focus Areas

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